Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373327 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Syntheses of 3,3-diheteroaromatic oxindole derivatives has been achieved by coupling indole-2,3-dione (isatin) with differently substituted indoles and pyrrole in presence of I2 in i-PrOH. The in vitro spermicidal potentials and the mode of spermicidal action of the synthesized analogues were evaluated and the derivative, 3,3-bis (5-methoxy-1H-indol-3-yl) indolin-2-one (3d) exhibited most significant activity.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Priyankar Paira, Abhijit Hazra, Shrabanti Kumar, Rupankar Paira, Krishnendu B. Sahu, Subhendu Naskar, Pritam saha, Shyamal Mondal, Arindam Maity, Sukdeb Banerjee, Nirup B. Mondal,