| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373421 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A new class of CETP inhibitors was designed and prepared. These compounds are potent both in vitro and in vivo. The most active compound (12d) has shown an ability to raise HDL significantly in transgenic mouse PD model.
Graphical abstractA new class of CETP inhibitors was designed and prepared. These compounds are potent both in vitro and in vivo. The most active compound (12d) has shown an ability to raise HDL significantly in transgenic mouse PD model.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhijian Lu, Joann B. Napolitano, Ashleigh Theberge, Amjad Ali, Milton L. Hammond, Eugene Tan, Xinchun Tong, Suoyu S. Xu, Melanie J. Latham, Laurence B. Peterson, Matt S. Anderson, Suzanne S. Eveland, Qiu Guo, Sheryl A. Hyland, Denise P. Milot, Ying Chen,