Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373458 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A novel series of potent and selective PPARδ agonists, para-alkylthiophenoxyacetic acids, was identified. The synthesis and structure–activity relationships are described.
Graphical abstractA series of para-alkylthiophenoxyacetic acids was prepared and found to be potent and selective PPARδ agonists.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rui Zhang, Aihua Wang, Alan DeAngelis, Patricia Pelton, Jun Xu, Peifang Zhu, Lubing Zhou, Keith Demarest, William V. Murray, Gee-Hong Kuo,