Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373490 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
The design and profile of a series of saligenin containing long acting β2-adrenoreceptor agonists is described. Evaluation of these analogues using a guinea-pig tissue model demonstrates that analogues within this series have significantly longer durations of action than salmeterol and have the potential for a once daily profile in human.
Graphical abstractThe design and profile of a series of saligenin containing long acting β2-adrenoreceptor agonists is described. Evaluation of these analogues using a guinea-pig tissue model demonstrates that analogues within this series have significantly longer durations of action than salmeterol and have the potential for a once daily profile in human.Figure optionsDownload full-size imageDownload as PowerPoint slide