| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373499 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
A new class of estrogen receptor beta (ERβ) ligands based on the 6H-chromeno[4,3-b]quinoline scaffold has been prepared. Several C7-substituted analogues displayed high affinity and modest selectivity for ERβ.
Graphical abstractA series of 6H-chromeno[4,3-b]quinolines has been prepared and displayed high affinity and moderate selectivity for estrogen receptor beta.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![ERβ ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor β-selective ligands](/preview/png/1373499.png "First Page Preview: ERβ ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor β-selective ligands")
Authors
An T. Vu, Alison N. Campbell, Heather A. Harris, Rayomand J. Unwalla, Eric S. Manas, Richard E. Mewshaw,