| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373559 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five of the test compounds showed significant lowering of plasma glucose level in STZ-S model.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Fateh V. Singh, Sumit Chaurasia, Maya D. Joshi, Arvind K. Srivastava, Atul Goel,