| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373583 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Through an in vivo screening model, we developed the in vivo SAR of β-alkylthio indolyl carbinols. Through these efforts we identified a compound with potent oral in vivo efficacy in both immature and mature rat prostate weight reduction models and in a murine xenograft prostate cancer model.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James C. Lanter, James J. Fiordeliso, Vernon C. Alford, Xuqing Zhang, Kenneth M. Wells, Ronald K. Russell, George F. Allan, Muh-Tsann Lai, Olivia Linton, Scott Lundeen, Zhihua Sui,