| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373601 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Eight members of a recently identified family of tetrahydrofuran-diols (THFDs), originating from epoxyeicosatrienoic acids (EETs), were prepared stereospecifically from d-(+)-glucose. The THFDs potently induced relaxation of pre-contracted bovine arteries.
Graphical abstractEight tetrahydrofuran-diols (THFDs), originating from epoxyeicosatrienoic acids (EETs), were prepared from d-(+)-glucose. THFD 10 was eqivalent to 14, 15-EET as a vasodilator of pre-contracted bovine arteries.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.R. Falck, L. Manmohan Reddy, Kihwan Byun, William B. Campbell, Xiu-Yu Yi,