| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373772 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Isosteric replacement of the amide function and modulation of the arylpiperazine moiety of known dopamine D3 receptor ligands led to potent and selective compounds. Enhanced bioavailability and preferential brain distribution make compound 6c a good candidate for pharmacological and clinical evaluation.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mickaël Jean, Jacques Renault, Nicolas Levoin, Denis Danvy, Thierry Calmels, Isabelle Berrebi-Bertrand, Philippe Robert, J.C. Schwartz, J.M. Lecomte, Philippe Uriac, Marc Capet,