| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373779 | Bioorganic & Medicinal Chemistry Letters | 2010 | 6 Pages |
Abstract
Additional SAR for an extended set of structural modification to key moieties of a novel series of selective kappa opioid receptor antagonists based on a previously disclosed series of 8-azabicyclo[3.2.1]octan-3-yloxybenzamides is described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2](/preview/png/1373779.png "First Page Preview: SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2")
Authors
Todd A. Brugel, Reed W. Smith, Michael Balestra, Christopher Becker, Thalia Daniels, Gerard M. Koether, Scott R. Throner, Laura M. Panko, Dean G. Brown, Ruifeng Liu, John Gordon, Matthew F. Peters,