| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373783 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Cyclam and DOTA-containing positron emission tomography radiotracers were prepared by using a modular chemical strategy based on peptide synthesis and chemoselective ligations. These molecules encompass two functional domains, one a tumour ‘homing’ domain and the other a chelating ligand for copper allowing nuclear imaging of tumours.
Graphical abstractPositron emission tomography radiotracer was prepared by using a modular chemical strategy and applied to the non-invasive nuclear imaging of tumours.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mathieu Galibert, Zhao-Hui Jin, Takako Furukawa, Toshimitsu Fukumura, Tsuneo Saga, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn,