Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373857 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A series of pyrazolylbisindole derivatives have been synthesized by reacting substituted pyrazole aldehydes with substituted indoles using phosphotungstic acid, a Keggin type heteropoly acid as catalyst. The synthesized pyrazolylbisindoles were evaluated for anti-microbial activities. The effect of pyrazolylbisindoles on the mycelial growth of plant pathogenic fungi is revealed. Entries 3c and 3d emerged as the most interesting compounds in this series exhibiting excellent anti-fungal activity.
Graphical abstractThe synthesis and anti-fungal activity of pyrazolylbisindoles is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ganesabaskaran Sivaprasad, Paramasivan T. Perumal, Vaiyapuri R. Prabavathy, Narayanasamy Mathivanan,