Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373864 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Fluorescence response upon hybridization of perylene labeled oligonucleotide probes depends on the microenvironment experienced by the perylene fluorophore. In mismatched duplex (PerU-C), enhanced fluorescence was observed while in matched duplex (PerU-A) fluorescence intensity decreased considerably. This observation will be a promising research effort in giving rise to a new powerful tool in detection of SNP.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Subhendu Sekhar Bag, Yoshio Saito, Kazuo Hanawa, Satoshi Kodate, Isamu Suzuka, Isao Saito,