Article ID Journal Published Year Pages File Type
1373864 Bioorganic & Medicinal Chemistry Letters 2006 4 Pages PDF
Abstract

Fluorescence response upon hybridization of perylene labeled oligonucleotide probes depends on the microenvironment experienced by the perylene fluorophore. In mismatched duplex (PerU-C), enhanced fluorescence was observed while in matched duplex (PerU-A) fluorescence intensity decreased considerably. This observation will be a promising research effort in giving rise to a new powerful tool in detection of SNP.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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