Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374066 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
We demonstrated an intriguing method to discriminate adenine by incident appearance of an intense new emission via exciplex formation in hybridization of target DNA with newly designed fluorescent 8-arylethynylated deoxyguanosine derivatives. We described the synthesis of such highly electron donating fluorescent guanosine derivatives and their incorporation into DNA oligomers which may be used for the structural study and the fluorometric analysis of nucleic acids.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yoshio Saito, Kenji Kugenuma, Makiko Tanaka, Azusa Suzuki, Isao Saito,