| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374077 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
A bio-inspired investigation of the reactions of substrates of type 1 with VOF3 and PIFA [phenyliodine(III) bis(trifluoroacetate)] led to a collection of colchicine-like compounds 2–5 and related systems. Biological evaluation revealed that some of the synthesized products had significant cytotoxic properties against the colon cancer cell line HT-29.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K.C. Nicolaou, Roman A. Valiulin, Jonathan K. Pokorski, Vicki Chang, Jason S. Chen,