| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374106 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A new polyaminocarboxylate ligand derived from N,C-pyrazolylpyridine was synthesized. The luminescence and relaxometry properties of its Tb3+ and Gd3+ chelates were investigated in aqueous solutions. The Tb3+ chelate is strongly luminescent having remarkable lifetime and quantum yield (τ = 1.82 ms and Φ = 0.42). The 1/T1 proton relaxivity at 20 MHz and 25 °C (5.3 s−1 mM−1) of the Gd3+ chelate was found to be comparable to that of the clinically used Gd-DTPA.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Claude Picard, Neri Geum, Isabelle Nasso, Béatrice Mestre, Pierre Tisnès, Sophie Laurent, Robert N. Muller, Luce Vander Elst,