| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374114 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC50 < 100 nM) and selectivity (SI > 1000) against the pestivirus BVDV (bovine viral diarrhea virus).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Gerhard Puerstinger, Jan Paeshuyse, Piet Herdewijn, Jef Rozenski, Erik De Clercq, Johan Neyts,