| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374120 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
A novel series of oxadiazole based amides have been shown to be potent DPP-4 inhibitors. The optimized compound 43 exhibited excellent selectivity over a variety of DPP-4 homologs.
Graphical abstractA novel series of oxadiazole-based amides have been shown to be potent DPP-4 inhibitors. The optimized compound 43 exhibited excellent selectivity over a variety of DPP-4 homologs.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jinyou Xu, Lan Wei, Robert J. Mathvink, Scott D. Edmondson, George J. Eiermann, Huaibing He, Joseph F. Leone, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Sangita B. Patel, Aleksandr Petrov, Giovanna Scapin, Joseph K. Wu,