| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374160 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A new group of serotoninergic 5-HT1A or 5-HT7 receptor ligands was identified. These compounds were designed and synthesized on a benzimidazolone scaffold and they enrich the well-known arylpiperazine class of 5-HT ligands. Diverse pharmacomodulations induced a shift in the affinity and selectivity profile with final identification of new potent hits.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eduard Badarau, Franck Suzenet, Andrzej J. Bojarski, Adriana-Luminiţa Fînaru, Gérald Guillaumet,