Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374174 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A series of pyrimidine nitrile inhibitors of Cathepsin K with reduced glutathione reactivity has been identified and Molecular Core Matching (MoCoM) has been used to quantify the effect of an amino substituent at C5.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andrew D. Morley, Peter W. Kenny, Brenda Burton, Robert A. Heald, Philip A. MacFaul, Julia Mullett, Ken Page, Soraya S. Porres, Lyn Rosenbrier Ribeiro, Phil Smith, Stuart Ward, Tina J. Wilkinson,