Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374200 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
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Related Topics
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Authors
Ulrika Nilsson, Mårten Jacobsson, Richard Johnsson, Katrin Mani, Ulf Ellervik,