Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374268 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A series of heterocyclic cycloalkanol ethylamines have been prepared to expand our norepinephrine reuptake inhibitor (NRI) program. Synthesis of a variety of heterocycles identified (+)-S-21, a potent NRI efficacious in an animal model for thermoregulatory dysfunction.
Graphical abstractA series of heterocyclic cycloalkanol ethylamines have been prepared to expand our norepinephrine reuptake inhibitor (NRI) program. Synthesis of a variety of heterocycles identified (+)-S-21, a potent NRI efficacious in an animal model for thermoregulatory dysfunction.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Joseph P. Sabatucci, Paige E. Mahaney, Jennifer Leiter, Grace Johnston, Kevin Burroughs, Scott Cosmi, Yingru Zhang, Douglas Ho, Darlene C. Deecher, Eugene Trybulski,