| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374295 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
The 7-alkene-3-quinolinecarbonitrile 20, a potent inhibitor of Src enzymatic and cellular activity with IC50 values of 2.1 and 58 nM, respectively, had comparable efficacy to bosutinib in a colon tumor xenograft study.
Graphical abstractThe 7-alkene-3-quinolinecarbonitrile 20, a potent inhibitor of Src enzymatic and cellular activity with IC50 values of 2.1 and 58 nM, respectively, had comparable efficacy to bosutinib in a colon tumor xenograft study.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Diane H. Boschelli, Daniel Wang, Yan Wang, Biqi Wu, Erick E. Honores, Ana Carolina Barrios Sosa, Inder Chaudhary, Jennifer Golas, Judy Lucas, Frank Boschelli,