| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374323 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Compounds 7e and 7f were the first in this series of benzoxazoles found to be a potent inhibitors of CETP (IC50 = 22 and 18 nM), with robust in vivo efficacy (ÎHDLc = 33 and 27 mg/dL) and absent of any hERG binding liabilities.
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Authors
Ramzi F. Sweis, Julianne A. Hunt, Peter J. Sinclair, Ying Chen, Suzanne S. Eveland, Qiu Guo, Sheryl A. Hyland, Denise P. Milot, Anne-Marie Cumiskey, Melanie Latham, Raymond Rosa, Larry Peterson, Carl P. Sparrow, Matt S. Anderson,