Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374379 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
An array of novel analogues of the marine oxylipins, the manzamenones and plakoridines, have been prepared in divergent fashion using an approach modelled on a biogenetic theory. Many of the target compounds show potent inhibition of DNA polymerases α and β and human terminal deoxynucleotidyl transferase (TdT).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jeremy R. Doncaster, Laura L. Etchells, Neil M. Kershaw, Ryoichi Nakamura, Hazel Ryan, Ryo Takeuchi, Kengo Sakaguchi, Ali Sardarian, Roger C. Whitehead,