Article ID Journal Published Year Pages File Type
1374389 Bioorganic & Medicinal Chemistry Letters 2006 4 Pages PDF
Abstract

A series of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-diones were synthesized through a rapid one-pot four-component reaction under microwave irradiation. The method has the advantages of excellent yields (82–96%) and short reaction time (4–9 min). We provide new series of potential biologically active compounds for biomedical screening.

Graphical abstractA series of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione derivatives for biomedical screening were synthesized under microwave irradiation.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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