Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374389 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A series of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-diones were synthesized through a rapid one-pot four-component reaction under microwave irradiation. The method has the advantages of excellent yields (82–96%) and short reaction time (4–9 min). We provide new series of potential biologically active compounds for biomedical screening.
Graphical abstractA series of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione derivatives for biomedical screening were synthesized under microwave irradiation.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shujiang Tu, Xiaotong Zhu, Jinpeng Zhang, Jianing Xu, Yan Zhang, Qian Wang, Runhong Jia, Bo Jiang, Junyong Zhang, Changsheng Yao,