| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374395 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The first mechanism-based inhibitor of a 3-deoxy-d-arabino heptulosonate 7-phosphate (DAH7P) synthase has been synthesised in 12 steps from d-arabinose, and has been found to be a very slow binding inhibitor of Escherichia coli DAH7P synthase.
Graphical abstractThe first mechanism-based inhibitor of a 3-deoxy-d-arabino heptulosonate 7-phosphate (DAH7P) synthase has been synthesised in 12 steps from d-arabinose, and has been found to be a very slow binding inhibitor of Escherichia coli DAH7P synthase.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Scott R. Walker, Emily J. Parker,