Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374465 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
An IKKβ inhibitor reported to block NF-κB transcriptional activities in Jurkat T cells, was found to enhance NF-κB translocation in HUVEC cells. These studies suggested a noncanonical NF-κB signaling pathway independent of IKKβ in HUVEC cells.
Graphical abstractA reported IKKβ inhibitor to inhibit NF-κB transcriptional activities in Jurkat T cells was found to enhance NF-κB translocation in HUVEC cells. These studies suggested a noncanonical NF-κB signaling independent to IKKβ in HUVEC cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gangli Gong, Yuli Xie, Yidong Liu, Alison Rinderspacher, Shi-Xian Deng, Yan Feng, Zhengxiang Zhu, Yufei Tang, Michael Wyler, Nathalie Aulner, Udo Toebben, Deborah H. Smith, Lars Branden, Caty Chung, Stephan Schürer, Dušica Vidović, Donald W. Landry,