| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374468 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A series of 2-(α-methylbenzylamino) pyrazines have shown to be potent inhibitors of the FMS tyrosine receptor kinase. Details of SAR studies, modeling and synthesis of compounds within this series are reported.
Graphical abstractA novel series of 2-(α-methylbenzylamino) pyrazines have been synthesized and shown to be potent inhibitors of the FMS tyrosine receptor kinase.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher J. Burns, Michael F. Harte, Xianyong Bu, Emmanuelle Fantino, Marilena Giarrusso, Max Joffe, Margarita Kurek, Fiona S. Legge, Pasquale Razzino, Stephen Su, Herbert Treutlein, Soo San Wan, Jun Zeng, Andrew F. Wilks,