Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1374628 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Cannabisin G (1), a naturally occurring lignanamide, was synthesized in 45% overall yield starting from 3-tert-butyl ethyl ferulate (6). An oxidative coupling by potassium ferricyanide in an alkaline media serves as the key step to construct the biphenylbutadiene skeleton of 1 with high regioselectivity.
Graphical abstractCannabisin G (1), a naturally occurring lignanamide, was synthesized in 45% overall yield starting from 3-tert-butyl ethyl ferulate (6). An oxidative coupling by potassium ferricyanide in an alkaline media serves as the key step to construct the biphenylbutadiene skeleton of 1 with high regioselectivity.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dawei Li, Wenling Li, Qian Wang, Zhaoqi Yang, Zijie Hou,