| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374725 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
Two new types of caged gene-inducers, caged 17β-estradiol and caged dexamethazone, were synthesized. Caged gene-inducers were applied to transgenic Arabidopsis plants carrying a steroid hormone-inducible transactivation system. Light uncaged caged gene-inducers and controlled spatial and temporal expression of transgene in the transgenic plant. Furthermore, caged gene-inducers enabled the control of root development by light.
Graphical abstractTwo caged steroids were synthesized as caged gene-inducers and applied to transgenic plants harboring steroid-inducible gene activation systems. Light could control the spatial and temporal expression of transgene and plant development.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ken-ichiro Hayashi, Kazuya Hashimoto, Naoyuki Kusaka, Atsushi Yamazoe, Hidehiro Fukaki, Masao Tasaka, Hiroshi Nozaki,