| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374741 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The elaboration of previously reported indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro inhibitory values for IMPDH II, PBMC proliferation and physicochemical properties are discussed.
Graphical abstractThe elaboration of previously reported indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro inhibitory values for IMPDH II, PBMC proliferation and physicochemical properties are discussed.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Rebekah E. Beevers, George M. Buckley, Natasha Davies, Joanne L. Fraser, Francis C. Galvin, Duncan R. Hannah, Alan F. Haughan, Kerry Jenkins, Stephen R. Mack, William R. Pitt, Andrew J. Ratcliffe, Marianna D. Richard, Verity Sabin, Andrew Sharpe,