| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374767 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A series of dihydropyrazolopyrimidine inhibitors of KV1.5 (IKur) have been identified. The synthesis, structure–activity relationships and selectivity against several other ion channels are described.
Graphical abstractA series of dihydropyrazolopryimidine inhibitors of KV1.5 (IKur) have been identified. The synthesis, structure–activity relationships and selectivity against several other ion channels are described.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wayne Vaccaro, Tram Huynh, John Lloyd, Karnail Atwal, Heather J. Finlay, Paul Levesque, Mary Lee Conder, Tonya Jenkins-West, Hong Shi, Lucy Sun,