| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374853 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stephanos Ioannidis, Michelle L. Lamb, Audrey M. Davies, Lynsie Almeida, Mei Su, Geraldine Bebernitz, Minwei Ye, Kirsten Bell, Marat Alimzhanov, Michael Zinda,