| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374967 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Structure–activity relationships and binding mode of novel heterocyclic factor VIIa inhibitors will be described. In these inhibitors, a highly basic 5-amidinoindole moiety has been successfully replaced with a less basic 5-aminopyrrolo[3,2-b]pyridine scaffold.
Graphical abstractThe structure activity relationships and binding mode of novel heterocyclic Factor VIIa inhibitors will be described. In these inhibitors, a highly basic 5-amidinoindole moiety has been successfully replaced with a less basic 5-aminopyrrolo[3,2-b]pyridine scaffold.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Roopa Rai, Aleksandr Kolesnikov, Paul A. Sprengeler, Steven Torkelson, Tony Ton, Bradley A. Katz, Christine Yu, John Hendrix, William D. Shrader, Robin Stephens, Ronnell Cabuslay, Ellen Sanford, Wendy B. Young,