| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1374986 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Constraining the catechol aryl ether moiety of bastadins by incorporation into a macrocyle is not necessary in order to mimic the effects of these marine natural products on neuronal calcium homeostasis. Simple, acyclic analogs that embody the ‘western’ or ‘eastern’ parts of bastadins were found to evoke comparable responses with bastadin 5.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Elzbieta Zieminska, Jerzy W. Lazarewicz, Elias A. Couladouros, Vassilios I. Moutsos, Emmanuel N. Pitsinos,