Article ID Journal Published Year Pages File Type
1375019 Bioorganic & Medicinal Chemistry Letters 2009 4 Pages PDF
Abstract

In this Letter we report the synthesis and in vitro studies of cleavable polymer–drug conjugates derived from dendritic polyglycerol and maleimide-bearing prodrugs of doxorubicin and methotrexate that are cleaved by cathepsin B. Cleavage properties and cytotoxicity of the new conjugates are presented.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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