Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375259 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
The 5″-branched cyclic ADP-carbocyclic-ribose derivatives were designed and synthesized. These target compounds were identified as the first antagonists of cADPR without a substituent at the adenine 8-position, and were shown to be stable due to the N1-carbocyclic-ribosyl structure.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natsumi Sakaguchi, Takashi Kudoh, Takayoshi Tsuzuki, Takashi Murayama, Takashi Sakurai, Akira Matsuda, Mitsuhiro Arisawa, Satoshi Shuto,