Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375383 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Novel fusapyrone analogs, deoxyneofusapyrone and 7-desmethyldeoxyneofusapyrone were isolated from a pathogenic fungus, Verticillium dahliae, which causes Verticillium wilt disease in Helianthus annuus. Spectral analyses revealed that these are 2-pyrone type analogs of deoxyfusapyrone and its 7-desmethyl derivative, respectively. Biological assay disclosed that 10 μg of deoxyneofusapyrone inhibited the growth of MRSA clinical isolate 87-7927.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Miho Honma, Shinji Kudo, Noboru Takada, Kazuaki Tanaka, Tomisato Miura, Masaru Hashimoto,