| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375396 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Proteins bearing a CaaL sequence are typically geranylgeranylated to enable their proper localization and function. We found that many of the dansyl-GCaaL peptides representing mammalian CaaL proteins can be farnesylated by FTase. This result may have important implications for prenylated protein biology.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Amanda J. Krzysiak, Animesh V. Aditya, James L. Hougland, Carol A. Fierke, Richard A. Gibbs,