Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375439 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
New Baylis–Hillman adducts are synthesized based on substituted 2-chloronicotinaldehydes and screened for their in vitro anti-malarial activity against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. Out of the six new compounds synthesized and screened, 2b, 2c and 2d compounds showed substantial anti-malarial activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
P. Narender, U. Srinivas, B. Gangadasu, Sukla Biswas, V. Jayathirtha Rao,