Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375442 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Cyclic enediynes 1a and 2a containing stable E-azo moiety (azoenediynes) have been synthesized. These compounds upon irradiation with long wavelength UV isomerize to the Z-compounds 1b and 2b, which can be thermally reisomerized to the Z compounds. Reactivity studies toward BC using DSC predictably indicate higher reactivity for the Z-isomers. Our studies may provide a novel way to modulate the reactivity of enediynes under thermal or photochemical conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Moumita Kar, Amit Basak, Manish Bhattacharjee,