| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375454 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
5,7-Disubstituted 4-heteroarylaminoquinazolines of the type above have been synthetised and evaluated as c-Src kinase inhibitors. Highly potent inhibition, high selectivity and physical properties suitable for oral dosing were achieved with this series.
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Authors
Bernard Barlaam, Mike Fennell, Hervé Germain, Tim Green, Laurent Hennequin, Rémy Morgentin, Annie Olivier, Patrick Plé, Michel Vautier, Gerard Costello,