Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375458 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
Manganese porphyrin systems carrying cyclodextrin binding groups can regioselectively and stereoselectively hydroxylate bound steroid substrates, using iodosobenzene as oxidant, but hydrogen peroxide and other simple oxidants such as sodium hypochlorite are not effective in water. Thiol ligands were then added to the catalyst, both covalently attached and hydrophobically bound, and with these ligands hydrogen peroxide was now an effective oxidant.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhenglai Fang, Ronald Breslow,