Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375589 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
Optimisation of a series of 4-piperidinyltriazoles led to the identification of compound 28a which showed good whole cell antiviral activity, excellent selectivity over the hERG ion channel and complete oral absorption.
Graphical abstractOptimisation of a series of compound 4-piperidinyltriazoles led to the identification of 28a which showed good whole cell antiviral activity, excellent selectivity over the hERG ion channel and complete oral absorption.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher G. Barber, David C. Blakemore, Jean-Yves Chiva, Rachel L. Eastwood, Donald S. Middleton, Kerry A. Paradowski,