Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375623 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
A series of benzyl phenyl ethers (BPEs) is described that displays potent inhibition of bacterial phenylalanyl-tRNA synthetase. The synthesis, SAR, and select ADMET data are provided.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Justin I. Montgomery, Peter L. Toogood, Kim M. Hutchings, Jia Liu, Lakshmi Narasimhan, Timothy Braden, Michael R. Dermyer, Angela D. Kulynych, Yvonne D. Smith, Joseph S. Warmus, Clarke Taylor,