Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375627 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
As part of an on-going lead optimisation effort, a cross screening exercise identified an aryl sulphonyl amide hit that was optimised to afford a highly potent series of ghrelin receptor agonists.
Graphical abstractAs part of an on-going lead optimisation effort, a cross screening exercise identified an aryl sulphonyl amide hit that was optimised to afford a highly potent series of ghrelin receptor agonists that displayed evidence of systemic exposure following oral administration.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jason Witherington, Lee Abberley, Benjamin R. Bellenie, Rio Boatman, Katharine Collis, David K. Dean, Alessandra Gaiba, N. Paul King, Nicola Shuker, Jon G.A. Steadman, Andrew K. Takle, Gareth Sanger, Sharon Butler, Fiona McKay, Alison Muir, Kim Winborn,