| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375630 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
3-Amido-4-anilinoquinolines are potent and highly selective inhibitors of CSF-1R. Their synthesis and SAR is reported, along with initial efforts to optimize the physical properties and PK through modifications at the quinoline 6- and 7-positions.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David A. Scott, Carrie L. Balliet, Donald J. Cook, Audrey M. Davies, Thomas W. Gero, Charles A. Omer, Srinivasu Poondru, Maria-Elena Theoclitou, Boris Tyurin, Michael J. Zinda,