| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1375633 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Four new dimeric sesquiterpene lactones japonicones A−D (1−4), comprised by eudesmane and guaiane sesquiterpenes, were isolated from the aerial part of Inula japonica Thunb. The structures and stereochemistry of 1−4 were elucidated by use of 2D NMR spectroscopic techniques, X-ray crystallography and modified Mosher method. Japonicone A (1) showed the most potent cytotoxicities against four tumor cell lines, A549, LOVO, CEM and MDA-MB-435.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jiang Jiang Qin, Hui Zi Jin, Jian Jun Fu, Xiao Jia Hu, Yan Wang, Shi Kai Yan, Wei Dong Zhang,