Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1375717 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
In the present paper, we successfully designed a series of potent aryl-piperazines as α1-AR antagonists based on a three-point pharmacophore. The 3D-QSAR study of this series of aryl-piperazines may provide some useful information for the designing of more potent aryl-piperazine analogues as α1-adrenoceptor antagonists.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Min-Yong Li, Hao Fang, Lin Xia,